Missouri is a U.S. state in the Midwest. Missouri is separated from Illinois and Kentucky, in the east by the Mississippi. Missouri also borders Iowa to the north, Kansas to the west, and Arkansas, Tennessee, and Oklahoma to the south. Missouri was the subject of the Missouri Compromise in the 1820s, which established Missouri's southern border as the line between free and slave states. Missouri fought for the Union during the American Civil War. Missouri still has a large agricultural sector, although it also has a considerable industrial base. Missouri's capital is Jefferson City, and its largest city is Kansas City.